It is the first time an Israeli prime minister will take the stand as a criminal defendant, an embarrassing milestone for a leader who has tried to cultivate an image as a sophisticated and respected statesman.
Netanyahu arrived at the packed courtroom ahead of his testimony, appearing at ease and shaking hands with members of his Likud party who were in attendance. Before taking the stand, Netanyahu's lawyer laid out the defense's case, and attempted to poke holes in the indictment.
Netanyahu will answer during his court appearances to charges of fraud, breach of trust and accepting bribes in three separate cases.
He is accused of accepting tens of thousands of dollars' worth of cigars and champagne from a billionaire Hollywood producer in exchange for assisting him with personal and business interests. He is also accused of promoting advantageous regulation for media moguls in exchange for favorable coverage of himself and his family.
Netanyahu, 75, denies wrongdoing, saying the charges are a witch hunt orchestrated by a hostile media and a biased legal system out to topple his lengthy rule. His testimony caps years of scandals that have swirled around him and his family.
"Eight years I've waited for this day. Eight years I have waited to present the truth. Eight years I am waiting to knock down once and for all these deluded and absurd charges against me," Netanyahu said defiantly on the eve of his testimony. "These investigations were born of sin. There was no offense, so they found an offense."
Dozens of people gathered outside of the court in Tel Aviv, some protesting against Netanyahu, including family members of hostages held in Gaza, and also a group of his supporters. A banner draped in front of the court read: "Crime Minister."
Under Israeli law, indicted prime ministers are not required to step down. But the charges against Netanyahu cleaved deep divisions in Israel, with protesters demanding he resign and former political allies refusing to serve in government with the Israeli leader, triggering a political crisis that led to five elections in less than four years beginning in 2019.
Netanyahu's supporters view the charges as the result of the justice system's bias and overreach.
Despite the pressure, the polarizing Netanyahu has rejected calls to step down and has used his position as prime minister to lash out at law enforcement, media and courts.
The testimony, set to take place six hours a day, three days a week for several weeks, will take up a significant chunk of Netanyahu's working hours, prompting critics to ask if he can capably manage a country embroiled in a war on one front, containing the fallout from a second, and keeping tabs on other potential regional threats, including from Iran or the recent fall of Bashar Assad in Syria.
An Israeli court rejected a request by Netanyahu's lawyers to reduce the expected testimony hours, as well as several other requests to delay the start of the testimony, which they said were necessary because of the prime minister's busy schedule and the country's significant challenges.