A team spokesperson said on Thursday that the team's departure time has been "slightly" delayed.
The hurricane brought powerful winds, a deadly storm surge and flooding to much of Florida after making landfall along the Gulf Coast as a Category 3 storm.
The Jaguars canceled a Friday press conference at the team hotel outside London and rescheduled it for Saturday morning. They play the Bears the next day at Tottenham Hotspur Stadium.
For their London games, the Jags regularly depart on Thursday night and arrive Friday morning.
On Wednesday, coach Doug Pederson expressed confidence in sticking to the travel plan
"It could affect some timing tomorrow trying to get out, but it looks good, it looks promising anyway, for our window to get out of here sort of on time with not too many delays or hiccups in the next 24 hours or so," he said.